tauprotein相关论文
目的:分析术前高压氧处理对冠状动脉搭桥术患者术后血清Tau蛋白、磷酸化Tau蛋白（pTau）及β-淀粉样蛋白1-42（Aβ1-42）水平的影响。方法:......
目的:观察n 18F-T807显像剂的安全性及其在阿尔茨海默病(AD)模型小鼠和正常老龄化小鼠体内的生物学分布。n 方法:选取无......
Aim: Alzheimers disease (AD) and other neurodegenerative dementia belong to a family of protein mis-folding diseases.The......
Tau hyperphosphorylation stimulated by GSK3 critically modulates chronic stress-induced depressive d
The hyperphosphorylation of Tau,a microtubule-associated protein,in the central nervous system has been shown as a remar......
Objective Alzheimers disease (AD) is one of the most common forms of neurodegenerative disease.Amyloid-β (Aβ) is consi......
Zinc Enhances the Formation of Liquid and Hydrogel Phases of Human Tau and thereby Increases Tau Tox
The homeostasis of zinc is fundamentally important in the CNS to ensure many physiological processes,but dyshomeostasis ......
Pathological concentration of zinc dramatically accelerates abnormal aggregation of full-length huma
A pathological hallmark of Alzheimer disease and other tauopathies is the formation of neurofibrillary tangles mainly co......
Advanced glycation end products (AGEs), products of the irreversible reaction of carbohydrates and protein in the Mailla......
Hyperphosphorylation of tau protein in the ipsilateral thalamus after focal cortical infarction in r
Objective To investigate changes of tau protein expression in the ipsilateral thalamus after distal middle cerebral arte......
Inhibition of anomalous aggregation of tau protein would be an attractive therapeutic target for Alzheimers disease (AD)......
Alzheimer\'s disease(AD)is an age-related neurodegenerative disease with two major hallmarks:extracellular amyloid pla......
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Probing the Molecular Origins of Cancer and Neurodegenerative Disease Using Time-Resolved Electrospr
Looking at the beautiful X-ray crystallographic protein structures that are the focus of classical structural biolog......
Study on the abnormal aggregation of Tau protein, and the ultrasensitiveselective detection of AD bi
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目的探讨经典抗抑郁药物西酞普兰对孤养导致的认知损害的改善作用与内在机制。方法60只8月龄的成年SD大鼠随机分组，分别予以群养(4......
Male Wistar 7-day-old rats were injected with 40 mg/kg ketamine intraperitoneally, followed by three additional injectio......
Neuroifbrillary tangles in Alzheimer’s disease：elucidation of the molecular mechanism by immunohisto
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期刊
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阿尔茨海默病（ AD）是一种慢性神经退行性疾病，β淀粉样蛋白（ Aβ）在海马过度沉积形成的老年斑是其主要的病理特点。 Aβ激活胶质细胞介......
目的 探究血清tau蛋白水平与新生儿缺血缺氧性脑病(hypoxic-ischemic encephalopathy,HIE)的严重程度及预后之间的关系.方法 测定......
p73基因是抑癌基因p53家族的一员,最先被认为与肿瘤的发生相关.近年来,研究者们发现p73基因与神经系统发育及神经系统变性疾病的病......
阿尔兹海默病(Alzheimer’s disease,AD)是一种常见的神经退行性疾病。农药作为环境污染物在其发生发展中起重要作用,研究农药与AD......
阿尔茨海默病(Alzheimers disease,AD)是一种以进行性痴呆(记忆减退、认知障碍以及人格改变1为临床特征,大脑皮质和海马区域出现细......
